Senior Design Teams
Biobloom's goal is to develop an at-home HPV test as a means of cervical cancer screening, targeting patients with traumatic histories or financial difficulties with current testing practices. Our novel solution uses menstrual blood and works seamlessly into the typical menstrual cycle.
Monday Morning Medical is developing a test strip that analyzes biomarkers for wound healing in an effort to provide concrete evidence of wound progression to the clinician. The test strip uses ELISA technology to analyze the concentration of MMP-2, a biomarker that increases to a a concentration of 0.22 µg/mL and then decreases in a wound that is healing normally. This solution will help clinicians determine when to remove surgical drains in order to limit infection and seroma of the wound.
Squish Labs is creating an implantable chemotherapeutic-infused hydrogel to treat residual tumor cells that cause recurrence in glioblastoma patients following tumor resection. Glioblastoma is the deadliest brain cancer and remains incurable, in part due to the challenge of achieving maximal resection. Additionally, many drugs cannot target the tumor effectively because of the selectivity of the blood-brain barrier. Gliadel is a carmustine wafer implant designed for post-resection treatment, but it failed to demonstrate sufficient efficacy for the FDA to approve it as a supplemental new drug. This device will address the shortcomings of Gliadel by sustaining therapeutic levels of drug in the resection cavity over several weeks.
Of the 320,000 cases of colectomy, a common colon reattachment surgical procedure to treat colon cancer performed yearly, about 18% leak following the surgery, causing life-threatening complications and repeat procedures with high mortality rates. The onset of these post-operative anastomotic leaks (AL) is still unknown; visible symptoms are often detected 5 to 7 days after surgery, but leaks may occur earlier. EnteroFlux proposes a continuous optical sensing system that notifies healthcare providers of an AL as early as 12 hours after the surgery while being noninvasive. Our device minimizes the likelihood of complications and improves patient outcomes.
Handm-aid is developing a cleaning device for laparoscopic instruments which ensures the removal of biofilm after a surgical procedure and before sterilization. This will lead to a reduced risk of infection from following procedures using laparoscopic instruments that have biofilm remaining after the current cleaning process.
WolfTronics is developing the Flow Defender, an electromechanical device to target the unmet medical need in the oxygen tank industry. Currently, oxygen tanks are set to a single physician-prescribed dosage which dosen't account for changes in patient metabolic state, which increases risk of hypoxia/oxygen poisoning. Our device takes input from pulse oximetry to adjust oxygen flow relative to the prescribed rate depending on respiratory state. This novel solution will improve the current process of oxygen delivery.
Our SteadySyringe aims to create a actuating arm holding device with a system for fluid control. This device provides an advantage for all clinicians who conduct one-handed syringe procedures in conjunction with other procedural tasks. Currently, competitive devices focus on the stabilization of the syringe for more precise injections, whereas the proposed solution specializes in maneuverability and ergonomics, allowing the clinician to multitask with better precision and stability.
Annie Kate Watson
Mederva Design is developing a novel wound management device to measure chronic wound conditions. WoundAware will alert patients when the wound environment is infected or a drop in moisture occurs. This device will allow healthcare workers to better treat chronic wounds and lower rates of serious infection.
Pediasalus is currently in development for an electrical stimulation device with which to facilitate bone growth. The device is intended to be used in treatment of pediatric limb length discrepancy. In causing bone growth specifically within the tibia, a noninvasive treatment option will be available for children with discrepancies due to a variety of origins.
The WolfHeels are developing a bronchoalveolar lavage assistive device that will decrease the number of specialized staff required to perform this procedure allowing for an increased number of clinicians available for an emergency situation in the ICU. The device will aid the clinician in the procedure by giving them more control of the irrigation and suction of fluid to and from the lungs. Our novel assistive device will be interchangeable with current infrastructure and will be reusable from one procedure to the next, thus saving clients' time and resources.
Devicentrics is developing an attachable device for the standard two-wheeled walker that allows for ease and reliablity of height adjustment as well as an increased base of support. This novel solution ensures healthcare professionals can consistently and efficiently change the height of the walker, as well as improves stability to reduce the risk of falling while ambulatory.
Accurate SpO2 levels are critical in monitoring infants' health, especially in infants with congenital heart defects or SIDS, who are underweight or premature. These situations can result in blood-oxygen levels decreasing, potentially causing cell death. PAW’s novel pediatric pulse oximeter is intended to be used at home to measure blood oxygen saturation levels in infants. The measurements will be taken over time from the forehead with electrical components housed in a beanie. The device will alarm if the infant’s SpO2 levels are abnormal. As PAW will go through the FDA approval process, our device will be considered a medical device.
Pediatrics association of wellness (PAW)
The Wet Bandits are developing a low-flow nasal cannula device for respiratory illnesses in pediatric hospital care to increase patient comfort and the adjustability of the device. Our solution improves the range of fit of the device by allowing children to lay flat on the back of their heads, enabling adjustability for various nose widths, and improving the attachment of the device to the face so instances of patient fussing are reduced. This device will lead to increased patient comfort and improve the process of providing patients with supplemental oxygen therapy.
NephroTech is developing a low-resource accessible urine microscopy kit, which can be useful for patients who need to monitor their glomerular kidney disease but who do not have easy access to a specialized nephrologist. The kit will combine a low-cost hand-powered centrifuge with a paper microscope. This solution can be useful in providing supplemental information for the patient and physician, increasing options for virtual/distance care, improving patient disease monitoring, and bettering patient long-term kidney health.
VR2OR is developing a surgery-specific virtual reality headset to improve the operating room field of view in Otolaryngology surgeons with age-related eyesight decline in order to reduce pediatric Tonsillectomy and Adenoidectomy post-op hemorrhage rates.
HMS Medical is developing a long range, wireless alert system to notify caregivers of critical life threats for at-home pediatric tracheostomy ventilator-dependent patients. The in-line pressure and flow sensors connect to the central hub, which continuously monitors the patient to detect life threats, such as accidental decannulation and obstruction. Upon detection, the hub sends wireless signals, via radio frequency, to a peripheral device that provides auditory, visual, and tactile modes of notification to promptly alert the caregiver. This product will provide primary caregivers flexibility away from the patient and improve intervention times in order to rapidly respond to life threats.
Poplar Health is developing a wearable device to quantify the cervical dilation diameter measurement taken while a pregnant patient is in labor, without disrupting the standard digital vaginal exam process. Our team’s solution will increase the accuracy of the measurement taken and remove the reliance on a clinician’s proprioception skill, leading to an improvement in labor progression tracking, a reduced number of exams, and a shorter clinician training process.
Our collaborator, Dr. Andrew Abumoussa, is currently developing an iOS application to assist with external ventricular drain (EVD) placement in order to improve accuracy of insertion. The application will be run on iOS devices, which must be positioned with the screen and camera facing in front of the patient without hindering the procedure. XR2OR is developing a mount to hold the device during the procedure that is designed to fit these specifications and tailored to surgical settings. This solution will provide the first step in implementing an XR navigation system in neurological procedures to reduce the risk of postoperative complications.
Vector is developing an active cooling method for blood during flight transport that provides consistent, monitored refrigeration. This new device will improve pre-hospital care capabilities by providing storage for more blood products in a lighter format. Access to more blood products will improve patient outcomes upon arrival to medical facilities and a lighter weight device will reduce fuel consumption to expand flight operations.
BioBlueprint is developing a surgical retractor for cleft palate/lip repair that is able to accommodate the atypical morphologies commonly present in these patients. This will reduce mean surgical time by improving the retractor fit, because improper fit commonly causes slippage that creates lacerations and increases surgical time.
Crescendo Technologies is committed to enhancing music perception for bilateral hearing-aid users with age-related hearing loss. While hearing aids can amplify high frequencies lost due to hair cell death in the basal end of the cochlea, they are designed for speech inputs and do not address worsened music perception. Our novel device uses a combination of signal processing and multisensory interaction to deliver rhythmic vibrations on the hearing-aid user's skin. This solution will lead to better music perception, measured by the Clinical Assessment of Music Perception (CAMP) test, and will improve quality of life as a result.
TBD Solutions is developing an adjustable tonal tinnitus therapy for students who experience distraction caused by their symptoms. Tonal tinnitus is a form of tinnitus where the perceived sound takes the form of a ringing or buzzing at a specific frequency. The novel ear-worn device will filter out the sound of the tinnitus throughout the day and act as a passive therapy to reduce symptoms with prolonged use.
Trusted by Design
MechanoMedical is developing a novel wrist brace, the AirFit Flex, designed for pediatric patients with spastic cerebral palsy during occupational therapy sessions. The AirFit Flex encourages a neutral wrist position through air inflation and leaves the palm uncovered. These design features enable the pediatric patient to develop independent grasping abilities with an occupational therapist through use of the fingers and tactile stimulation to the palm.
GoldiFlex is a team united over a shared interest in biomechanics, specifically in the development of products that can more actively prevent and reduce the impact of sports related injuries. We quickly discovered a large gap in the current market for ankle support devices during the recovery process. We have decided to address the need of providing adjustable support and flexibility at the ankle within proper physiological range of motion while conversely providing highly rigid support outside of these ranges for athletes that have sustained an ankle sprain in order to reduce the risk of reinjury.
Cathetero aims to develop surgical tools to facilitate the accurate placement of catheters or guide wires. The designed tools can improve current equipment's navigational ability so physicians can rapidly reach desired areas inside patients with higher accuracy during ERCP. This novel approach would give physicians more information during ERCP to reduce the number of failed attempts, which can reduce post-ERCP complications.